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黃曉華(外聘)

黃曉華   性別:女 出生日期:1958年10月1日 職稱:教授 聯系電話:025-85891651(辦公) 電子郵件:huangxiao@njnu.edu.cn

【學術簡介】

〖學習經歷〗:1978-1982于安徽師范大學化學系學習;1985-1987在北京大學化學系研究生課程學習。〖研究經歷〗:1991 -1992在北京大學作高級訪問學者;1994為碩士生導師;2003為博士生導師。〖學術及社會兼職〗:2006年兼聘國家發改委稀土專家;2008年兼聘江蘇省高級人民法院知識產權廳專家及其人民陪審員;2009年兼聘稀土化學農醫專業委員會副主任等。

【主講課程】

博士研究生:

碩士研究生:

本 科 生:

【指導碩、博士生研究方向】

亚博全网博士研究生:從事化學與生物學交叉研究領域,主要研究方向為生物無機化學,即將生物物理化學研究手段、細胞化學方法與細胞生物學技術優化組合,研究稀土元素、重金屬離子、醫用納米材料對細胞及其生物酶分子的結構、功能及其微觀化學過程的影響。

亚博全网碩士研究生:從事化學與生物學交叉研究領域,主要研究方向為生物無機化學,即將生物物理化學研究手段、細胞化學方法與細胞生物學技術優化組合,研究稀土元素、重金屬離子、醫用納米材料對細胞及其生物酶分子的結構、功能及其微觀化學過程的影響。

【研究領域】

從事化學與生物學交叉研究領域,主要研究方向為生物無機化學,即將生物物理化學研究手段、細胞化學方法與細胞生物學技術優化組合,研究稀土元素、重金屬離子、醫用納米材料對細胞及其生物酶分子的結構、功能及其微觀化學過程的影響。

【主要論著】

亚博全网(1) Na Jiang, Lihong Wang, Chunlei Du, Xiaolan Ding, Xiaohua Huang*. The formation of a new horseradish peroxidase binding rare earth. Environ. Chem. Lett.2011.9(2):191-196.

(2) Wenbo Zhao, Guohui Zhang, Lancao Jiang, Tianhong Lu, Xiaohua Huang∗, Jian Shen∗. Novel polyurethane ionomer nanoparticles displayed a good biosensor effection. Colloids and Surfaces B: Biointerfaces.2011, 88 : 78–84.

(3) Guohui Zhang,Yi Fang, Jian Shen, Chun Mao∗, Xiaohua Huang∗. Cytocompatible Performance of Thermosensitive Poly(N-Isopropylacrylamide) Nanoparticles. Journal of Biomaterials Science. 2011, 1–10.

亚博全网(4) Guohui Zhang, Ningbo Yang, Yalong Ni, Jian Shen, Wenbo Zhao∗, Xiaohua Huanga∗. A H2O2 electrochemical biosensor based on biocompatible PNIPAM-g-P(NIPAM-co-St) nanoparticles and multi-walled carbon nanotubes modi?ed glass carbon electrode. Sensors and Actuators B. 2011,158 : 130–137.

(5) Zhenping Chen, Dongmei Sun∗, Yiming Zhou, Jiayue Zhao, Tianhong Lu, Xiaohua Huang∗,Chenxin Cai, Jian Shen. Nano polyurethane-assisted ultrasensitive biodetection of H2O2 over immobilized Microperoxidase-11.Biosensors and Bioelectronics.2011,29:53-59.

(6) Wang L, Jiang N, Zhao B, Li X, Lu T, Huang X∗. Structural basis for the decrease in the outward potassium channel current induced by lanthanum. Journal of Biological Inorganic Chemistry. 2010,15(7):989-993.

(7) Wang L, Zhou Q, Lu T, Ding X, Huang X*. Molecular and cellular mechanism of the effect of La(III) on horseradish peroxidase. Journal of Biological Inorganic Chemistry. 2010, 15(7):1063-1069.

亚博全网(8) Lihong Wang, Aihua Lu, Tianhong Lu, Xianlan Ding, Xiaohua Huang*. Interaction between lanthanum ion and horseradish peroxidase in vitro. Biochimie. 2010,15(7):989-993.

(9) Wang LH, Zhou Q, Zhao B, Huang XH* .Toxic effect of heavy metal terbium ion on cell membrane in horseradish. Chemosphere. 2010,80:28-34.

亚博全网(10) Wang LH, Zhou Q*, Huang XH* Effects of heavy metal terbium on contents of cytosolic nutrient elements in horseradish cell Ecotoxicology and Environmental Safety. 2010,73:1012-1017.

(11) Guo SF, Wang LH, Lu TH, Ding XL, Huang XH∗. Direct electrochemistry and electrocatalysis of complex of horseradish peroxidase and La (III) at nano-gold colloid/cysteine/gold. Electrode Journal of Electroanalytical Chemistry. 2010, 644(1):80-84.

(12) Wenru Wu,Yuzhi Rong,Bo Zhao,Peipei Sun*,Xiao hua Huang* The study on the interaction between Tb(III) and ligand in Tb–acetylsalicylic acid complex and ?uorescence mechanism. Journal of Luminescence. 2010,130:92-95.

亚博全网(13) Guo SF, Wang LH, Lu AH, Lu TH, Ding XL, Huang XH∗ Inhibition mechanism of lanthanum ion on the activity of horseradish peroxidase in vitro. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2010,75(2): 936-941

(14) Xiaohua Huang, Qing Zhou, Tianhong Lu,Shaofen Guo. Design and preparation of plant growth regulator of rare earth element-amino acid-vitamine, 2009, United States Patent(EFSID;4978659;PCT/CN07/01912).

亚博全网(15) Mao, C., Jiang, L.C., Luo, W.P., Liu, H. K., Bao, J. C., Huang, X. H*., Shen, J*. Novel Blood-Compatible Polyurethane Ionomer Nanoparticles. Macromolecules. 2009, 42 (23): 9366–9368..

(16) Lihong Wang, Qing Zhou, Xiaohua Huang*. Photosynthetic responses to heavy metal terbium stress in horseradish leaves. Chemosphere. 2009, 77:1019-1025.

亚博全网(17) Shaofen Guo, Lihong Wang, Aihua Lu , Tianhong Lu , Xiaolan Ding, Xiaohua Huanga*.Inhibition mechanism of lanthanum ion on the activity of horseradish peroxidase in vitro. Spectrochimica Acta Part A. 2009, SAA-7462.

(18) Wang, L.H., Huang, X.H.*, Zhou, Q.* Effects of Rare Earth Elements on the Distribution of Mineral Elements and Heavy Metals in Horseradish. Chemosphere. 2008,73(3): 314-319.

(19) Shaofen Guo, Xiaolan Ding, Tianhong Lu, Qing Zhou, Xiaohua Huang*. Inhibition Mechanism of Tb(III) on Horseradish Peroxidase Activity in vitro Chemistry & Biodiversity. 2008, 5: 2050-2059.

亚博全网(20) Shaofen Guo, Qing Zhou, Tianhong Lu, Xiaolan Ding, Xiaohua Huang*. One of the Possible Mechanism for the Inhibition Effect of Tb(III) on Peroxidase Activity in Horseradish (Armoracia rusticana)Treated with Tb(III). Journal of Bioogical Inorganic Chemistry. 2008, 13:587-597.

亚博全网(21) Yaxin Ye, Lihong Wang, Xiaohua Huang*, Tianhong Lu, Xiaolan Ding, Qing Zhou. Subcellular Location of Horseradish Peroxidase in Horseradish Leave Treated with La(III), Ce(III) and Tb(III). Ecotoxicology and Environmental Safety. 2008, 71:677-684.

亚博全网(22) Liu, H.K. *, Huang, X.H.*, Lu, T.H., Wang, X.J., Sun, W.Y., Kang, B.S. Discrete and Infinite 1d, 2d/3d Cage Frameworks with Inclusion of Anionic Species and Anion-Exchange Reactions of Ag3l2 Type Receptor with Tetrahedral and Octahedral Anions. Dalton Transactions. 2008, (24): 3178-3188.

(23) Shaofen Guo, Xiaohua Huang*, Tianhong Lu ,Xiaolan Ding, Qing Zhou. Spectroscopic studies of interactions involving horseradish peroxidase and Tb3+. Spectrochimica Acta Part A. 2008, 70: 818-823.

(24) Hui Zhou, Tianhong Lu, Hongxia Shi, Zhihui Dai, Xiaohua Huang*. Direct electrochemistry and electrocatalysis of catalase immobilized on carbon nanotubes modified glassy carbon electrode and its appilication. Journal of Electroanalytic Chemistry. 2008, 612: 173-178.

亚博全网(25) Xiaoyun Guo, Mingqing Chen, Tianhong Lu, Xiaohua huang*. Effect of Tb(III) on the properties of P(NIPAM-co-St) copolymer microsphere. Journal of Polymer Research.2008, 15: 141-145.

(26) Xiaoshan Guo, Qing Zhou, Tianhong Lu, Min Fang, and Xiaohua Huang*. Distribution and translocation of 141Ce(III) in horseradish. Annals of Botany. 2007, 100:1459-1465.

(27) Guo, S.F., Zhou, Q., Lu, T.H., Ding, X.L., Huang, X.H.* Inhibition Effect of Tb(III) on Horseradish Peroxidase Activity. Journal of Biological Inorganic Chemistry. 2007,12, (S1): S203.

亚博全网(28) Shaofen Guo, Qing Zhou, Tianhong Lu, Xiaolan Ding, Xiaohua Huang*. Interaction between La3+ and MP-11 in the physiological solution. Electrochimica Acta. 2007,52: 2032-2038.

(29) Xiaohua Huang *, Shaofen Guo, Qing Zhou, Tianhong Lu, Xiaolan Ding. Effect of La3+ on structure and electrochemical reaction of microperoxidase-11 in imitated physiological solution. Journal of Electroanalytic Chemistry. 2007, 600: 227–235.

(30) Weiqing Yin, Mingqing Chen, Tianhong Lu, Mitsuru Akashi, Xiaohua Huang*. Properties of complex of Tb(III) and poly(N-isopropylacrylamide)-g-poly(N-isopropylacrylamide-co-styrene) core-shell nanoparticles. Journal of Alloys and Compounds. 2007, 432: L18–L21.

【科研項目】

(1)江蘇省自然科學基金-重金屬Tb作用于植物細胞膜的微觀化學行為研究(BK2009401)(2009-2012);

亚博全网(2)江蘇省工業支撐計劃項目-聚氨酯無機仿生表面構建的關鍵技術及生物醫用研究(BE2009164)(2009-2012);

亚博全网(3)國家自然科學基金項目-稀土作用于辣根細胞膜的若干生物無機化學行為研究(20971069)(2010-2012);

(4)“211工程”三期建設項目-特異生物功能化合物的分子設計(20090211)(2009-2013)。

亚博全网(5)中央財政支持地方高校發展專項資金項目(2010~2013)。

【科研成果及獎勵】

作為項目主持人近三年來, 完成中美合作項目、國家自然科學基金、國家發改委、江蘇省高技術及教育部重點項目等8項、在研項目3項。

在J.Biol.Inorg.Chem., J.Phys.Chem., Dalton Transactions, Ecotoxicology and Environmental Safety, Annals of Botany,Electrochimica Acta., J. Electro. Chem.,J. Mater. Chem.等學術期刊上合作發表SCI論文60余篇(其中第一及通信作者42篇)。被國外SCI期刊如Journal of Physical Chemistry(B、C), Dalton Transactions, International Journal of Biological Sciences, Biological Trace Element Research, Langmuir, Ecotoxicology and Environmental Safety, Annals of Botany, Environmental Chemistry Letters等他引223次,單篇最高引用17次。

2007年應邀在 “13th International Conference on Biological Inorganic Chemistry(ICBIC13,維也納)”會上報告;2009年又收到“ICBIC14,日本”會議報告的邀請。

【所獲專利】

獲得1項美國專利及6項中國(授權)發明專利。其中,一項特色研究成果用于出口經濟作物,05-07連續三年該產品獲得歐盟生態證書及出口美國、加拿大、丹麥、德國等國家和地區,凈增經濟效益96萬美元。

【在讀碩、博士人數】

 

【已畢業碩、博士人數】

 

【指導本科生人數】

 

【以上資料更新日期】